<p style="text-align: center;">XU Nenggui，Zhang Lizhi&nbsp;</p><p style="text-align: center;">(Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine,&nbsp;</p><p style="text-align: center;">Guangzhou, 510006, China )</p><p><strong>Abstract</strong>: The article aims to introduce Professor Xu Nenggui&#39;s &quot;Du pulse for the brain, attending the brain disease&quot; academic thinking. To elucidate the theoretical basis and mechanism of the treatment of ischemic stroke.&nbsp; I&nbsp; believe&nbsp; that&nbsp; pass&nbsp; the&nbsp; tone&nbsp; of&nbsp; the&nbsp; needle&nbsp; in&nbsp; the&nbsp; clinical&nbsp; treatment&nbsp; of&nbsp; stroke&nbsp; and&nbsp; its&nbsp; sequelae significantly, should be further clinical research and application.</p><p><strong>Key words</strong>: Acupuncture and moxibustion, pass the regulation of the needle; Xu Nengui; theoretical basis; mechanism of action</p><p><br/></p>