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The application of the Animal Energy Metabolism Monitoring System (AEMMS) in the interventions of acute alcoholic liver injury by acupuncture

作者:孙梦晓 来源:本站原创 点击:25次 更新:2018-05-02

LI Shunyue,SONG Xiaojing,WANG Shuyou,ZHANG Dong

(1.Institute of Acupuncture and Moxibustion, Chinese Academy of Chinese Medical Sciences, Beijing 100070)

AbstractObjective:  To  explore  the  value  of  using  the  animal  energy  metabolism  monitoring  system (AEMMS) in the study to improve  the energy metabolism of  acute alcohol liver injury in rat by acupuncture. Methods: 30 rats were divided into control group, model group and EA group randomly. Model group and EA group were  gavaged  with 50% ethanol (12ml / kg), which were resulting in an animal model of acute alcoholic  liver  injury.  EA  group  after  gavaged  was  treated  30min  each  time  every  day  by  acupuncture Zusanli(ST -36),  and  the  treatment  continued  3  days.  To  observe  the  RER,  heat,  feeding  and  drinking continuously  for  96h  in  each  group  at  same  time  by  AEMMS.  Results:  The  RER,feeding  and  drinkingdecreased significantly in rats with ALI,the heat in which increased;There was an increased tendency of the  RER, feeding and drinking,and an declined tendency of the heat in model rats by EA intervention.  Conclusion:  It was  indicated  that  there was a  practical value  of AEMMS through the study of the energy metabolism of rats with ALI by acupuncture. 

Key words: Acupuncture and moxibustion, Liver injury, energy metabolism


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